FOLR2 Protein (AA 17-228) (mFc Tag)
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- 抗原 See all FOLR2 蛋白
- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 17-228
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FOLR2 protein is labelled with mFc Tag.
- 原理
- Recombinant human FOLR2 protein with C-terminal mouse Fc tag
- 特异性
- FOLR2 (Thr17-His228) mFc (Pro99-Lys330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product FOLR2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
- 别名
- FOLR2 (FOLR2 产品)
- 别名
- FOLR2 Protein, BETA-HFR Protein, FBP Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FBP2 Protein, Folbp-2 Protein, Folbp2 Protein, folate receptor 1 Protein, folate receptor beta Protein, folate receptor 2 (fetal) Protein, FOLR1 Protein, FOLR2 Protein, Folr2 Protein
- 背景
- The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- 分子量
- predicted molecular mass of 50.7 kDa after removal of the signal peptide.The apparent molecular mass of FOLR2-mFc is 35-55 kDa due to glycosylation.
- UniProt
- P14207
- 途径
- Dicarboxylic Acid Transport
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