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Tissue factor Protein (AA 33-251) (His tag)

F3 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN7013638
发货至: 中国
  • 抗原 See all Tissue factor (F3) 蛋白
    Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 33-251
    宿主
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    资源
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Tissue factor protein is labelled with His tag.
    产品特性
    Human Coagulation Factor III / Tissue Factor Protein, His Tag (MALS verified)
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product F3 蛋白
  • 应用备注
    MALS verified
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 150 mM NaCl, pH 7.5
    储存条件
    -20 °C
  • 抗原
    Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
    别名
    Coagulation Factor III (F3 产品)
    别名
    CD142 Protein, TF Protein, TFA Protein, PRO1557 Protein, PRO2086 Protein, TFQTL1 Protein, f3 Protein, AA409063 Protein, Cf-3 Protein, Cf3 Protein, tf Protein, zgc:112151 Protein, coagulation factor III, tissue factor Protein, transferrin Protein, coagulation factor IIIa Protein, coagulation factor III Protein, tissue factor Protein, coagulation factor IIIb Protein, coagulation factor III (thromboplastin, tissue factor) S homeolog Protein, F3 Protein, TF Protein, f3a Protein, tf Protein, f3b Protein, f3.S Protein
    背景
    Full-length tissue factor (TF) is a transmembrane receptor and cofactor for factor (F)VII/FVIIa. In addition to full-length TF, an alternative spliced (as) form of TF can be generated that lacks the transmembrane domain and is released fromcells. In contrast to TF, asTF has low procoagulant activity because it lacks the transmembrane domain. Tissue factor is expressed by cells around blood vessels, such as adventitial fibroblasts, and body surfaces, such as epithelial cells, and plays a critical role in hemostasis. TF also contributes to various forms of thrombosis. Many cancers, particularly adenocarcinomas, express high levels of TF. A high level of tumor TF expression is associated with poor prognosis in many types of cancers, including breast, prostate, colorectal, and pancreatic cancer.
    分子量
    26.7 kDa
    NCBI登录号
    NP_001984
    途径
    Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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