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Topoisomerase II alpha Protein (AA 1354-1473)

This Recombinant Topoisomerase II alpha protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7013599
发货至: 中国
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Quick Overview for Topoisomerase II alpha Protein (AA 1354-1473) (ABIN7013599)

抗原

See all Topoisomerase II alpha (TOP2A) 蛋白
Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

蛋白类型

Recombinant

宿主

  • 6
  • 1
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资源

  • 3
  • 2
  • 1
大肠杆菌(E. Coli)

纯度

>90 % as determined by SDS-PAGE.
  • 产品特性

    AA 1354-1473

    序列

    AA 1354-1473

    产品特性

    Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    50 mM Tris, 0.5 M KCl, pH 8.0

    储存条件

    -80 °C
  • 抗原

    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

    别名

    TOP2A

    背景

    DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.

    分子量

    12.8 kDa

    NCBI登录号

    NP_001058

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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