MGC84748 Protein, FGL1 Protein, DKFZp470A2333 Protein, Frep1 Protein, Lfire1 Protein, HFREP1 Protein, HP-041 Protein, LFIRE-1 Protein, LFIRE1 Protein, Mfire1 Protein, fibrinogen like 1 L homeolog Protein, fibrinogen like 1 Protein, fibrinogen-like 1 Protein, fibrinogen-like protein 1 Protein, fgl1.L Protein, FGL1 Protein, Fgl1 Protein
背景
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.