CD8 Protein (CD8) (AA 22-182) (His tag)
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- 抗原 See all CD8 蛋白
- CD8
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 22-182
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD8 protein is labelled with His tag.
- 产品特性
- Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- 应用备注
- MALS verified
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- CD8
- 别名
- CD8 alpha & beta (CD8 产品)
- 别名
- CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, CD8a molecule Protein, CD8A Protein
- 背景
- Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
- 分子量
- 19.5 kDa (CD8A) & 22.1 kDa (CD8B)
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