SLAMF8 Protein (AA 23-233) (His tag,AVI tag,Biotin)
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- 抗原 See all SLAMF8 蛋白
- SLAMF8 (SLAM Family Member 8 (SLAMF8))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 23-233
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SLAMF8 protein is labelled with His tag,AVI tag,Biotin.
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- Biotinylated Human BLAME / SLAMF8 Protein, His,Avitag™
- 纯度
- >85 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product SLAMF8 蛋白
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- 说明
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Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Sodium Citrate, 150 mM NaCl, pH 5.5
- 储存条件
- -20 °C
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- 抗原
- SLAMF8 (SLAM Family Member 8 (SLAMF8))
- 别名
- BLAME (SLAMF8 产品)
- 别名
- BLAME Protein, CD353 Protein, SBBI42 Protein, 5830408F06Rik Protein, Blame Protein, SLAM family member 8 Protein, Slamf8 Protein, slamf8 Protein, SLAMF8 Protein
- 背景
- BLAME (B-lymphocyte activator macrophage expressed) is also known as SLAM family member 8(SLAMF8), CD353. BLAME is a cell surface receptor that is expressed upon activation of macrophages (Ms) by IFN-γ or bacteria, is a negative regulator of ROS in response to Gram+ and Gram- bacteria. May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. SLAMF8 is a costimulatory molecule that affects the activation of macrophages in inflammation and in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.
- 分子量
- 27.1 kDa
- NCBI登录号
- NP_064510
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