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Ret Proto-Oncogene Protein (RET) (Fc Tag)

RET 宿主: 人 宿主: HEK-293 Cells Recombinant
产品编号 ABIN6964355
发货至: 中国
  • 抗原 See all Ret Proto-Oncogene (RET) 蛋白
    Ret Proto-Oncogene (RET)
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    资源
    • 2
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    HEK-293 Cells
    标记
    This Ret Proto-Oncogene protein is labelled with Fc Tag.
    序列
    RET (Leu29-Arg635)+hFc(GLU99-ALA330)
    产品特性
    Tagged Protein: C-Human Fc tag
    纯化方法
    affinity purification
    Top Product
    Discover our top product RET 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -80 °C
    储存方法
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    有效期
    12 months
  • 抗原
    Ret Proto-Oncogene (RET)
    别名
    RET (RET 产品)
    别名
    c-ret Protein, cret Protein, etID315074.13 Protein, ret1 Protein, wu:fd13h01 Protein, X-ret Protein, ret-A Protein, xret Protein, RET Protein, MTC1 Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, RET9 Protein, c-Ret Protein, ret proto-oncogene receptor tyrosine kinase Protein, ret proto-oncogene S homeolog Protein, ret proto-oncogene Protein, ret Protein, ret.S Protein, RET Protein, Ret Protein
    背景
    Synonymes: CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1
    Description: This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. [provided by RefSeq, Sep 2017]
    分子量
    92.29 kDa
    UniProt
    P07949
    途径
    RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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