CD51 Protein (AA 31-992) (Fc-His Tag)
ITGAV
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 抗原 See all CD51 (ITGAV) 蛋白
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-992
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD51 protein is labelled with Fc-His Tag.
- 原理
- Recombinant heterodimer protein containg both human ITGAV Protein with C-terminal 6xHis tag and human ITGB1 protein with C-terminal human Fc tag
- 序列
- ITGAV(Phe31-Val992)+ ITGB1(Gln21-Asp728)+hFc(Glu99-Ala330)
- 特异性
- ITGAV (Phe31-Val992) 6xHis tag - ITGB1 (Gln21-Asp728) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ITGAV 蛋白
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Integrin alpha V (ITGAV) (AA 1-1048) protein (GST tag)
ITGAV 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- 别名
- ITGAV (ITGAV 产品)
- 别名
- 1110004F14Rik Protein, 2610028E01Rik Protein, CD51 Protein, D430040G12Rik Protein, MSK8 Protein, VNRA Protein, VTNR Protein, Cd51 Protein, integrin subunit alpha V Protein, integrin alpha V Protein, ITGAV Protein, Itgav Protein
- 背景
- Integrin alpha-5/beta-1 is a receptor for ibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-V/beta-1 is also a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition.
- 分子量
- predicted molecular mass of 107.1 and 104.5 kDa after removal of the signal peptide. The apparent molecular mass of ITGAV-His and ITGB1-hFc is 130-250 kDa due to glycosylation.
- UniProt
- P06756, P05556
- 途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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