90K Protein, BTBD17B Protein, MAC-2-BP Protein, TANGO10B Protein, Ppicap Protein, CyCAP Protein, MAC-2BP Protein, Tango10b Protein, lgals3bp Protein, zgc:136780 Protein, MAC2BP Protein, Mac-2 BP Protein, zgc:77059 Protein, galectin 3 binding protein Protein, lectin, galactoside-binding, soluble, 3 binding protein Protein, calcium activated nucleotidase 1 Protein, lectin, galactoside-binding, soluble, 3 binding protein a Protein, lectin, galactoside-binding, soluble, 3 binding protein b Protein, LGALS3BP Protein, Lgals3bp Protein, CANT1 Protein, lgals3bpa Protein, lgals3bpb Protein
背景
Synonymes: 90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B Description: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.