C5AR1 Protein (AA 1-37) (Fc Tag)
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- 抗原 See all C5AR1 蛋白
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-37
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This C5AR1 protein is labelled with Fc Tag.
- 原理
- Recombinant Human C5AR1 Protein with C-terminal human Fc tag
- 特异性
- C5AR1 (Met1-Asp37) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product C5AR1 蛋白
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Complement Component 5a Receptor 1 (C5AR1) protein
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Complement Component 5a Receptor 1 (C5AR1) protein (Myc-DYKDDDDK Tag)C5AR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- 别名
- C5AR1 (C5AR1 产品)
- 别名
- C5A Protein, C5AR Protein, C5R1 Protein, CD88 Protein, C5aR Protein, C5r1 Protein, Cd88 Protein, D7Msu1 Protein, GPR77 Protein, complement C5a receptor 1 Protein, complement component 5a receptor 1 Protein, C5AR1 Protein, C5ar1 Protein, c5ar1 Protein
- 背景
- Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
- 分子量
- predicted molecular mass of 30.4 kDa after removal of the signal peptide.The apparent molecular mass of C5AR1-hFc is 40-53 kDa due to glycosylation.
- UniProt
- P21730
- 途径
- Complement System
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