Mesothelin Protein (MSLN) (AA 296-580) (mFc-His Tag)
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- 抗原 See all Mesothelin (MSLN) 蛋白
- Mesothelin (MSLN)
- 蛋白类型
- Recombinant
- 产品特性
- AA 296-580
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Mesothelin protein is labelled with mFc-His Tag.
- 应用范围
- Western Blotting (WB)
- 原理
- Recombinant human Mesothelin(296-580) protein with C-terminal mouse Fc and 6xHis tag
- 特异性
- Mesothelin (Glu296-Gly580) mFc (Pro99-Lys330) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MSLN 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Mesothelin (MSLN)
- 别名
- Mesothelin (MSLN 产品)
- 别名
- MPF Protein, SMRP Protein, MSLN Protein, mesothelin Protein, MSLN Protein, Msln Protein, LOC611363 Protein, LOC100524016 Protein
- 背景
- This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- 分子量
- predicted molecular mass of 59.3 kDa after removal of the signal peptide.
- 基因ID
- 10232
- UniProt
- Q13421
- 途径
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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