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Mesothelin Protein (MSLN) (AA 296-580) (mFc-His Tag)

MSLN 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. WB
产品编号 ABIN6961104
发货至: 中国
  • 抗原 See all Mesothelin (MSLN) 蛋白
    Mesothelin (MSLN)
    蛋白类型
    Recombinant
    产品特性
    AA 296-580
    宿主
    • 47
    • 14
    • 4
    • 2
    资源
    • 44
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Mesothelin protein is labelled with mFc-His Tag.
    应用范围
    Western Blotting (WB)
    原理
    Recombinant human Mesothelin(296-580) protein with C-terminal mouse Fc and 6xHis tag
    特异性
    Mesothelin (Glu296-Gly580) mFc (Pro99-Lys330) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product MSLN 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Mesothelin (MSLN)
    别名
    Mesothelin (MSLN 产品)
    别名
    MPF Protein, SMRP Protein, MSLN Protein, mesothelin Protein, MSLN Protein, Msln Protein, LOC611363 Protein, LOC100524016 Protein
    背景
    This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    分子量
    predicted molecular mass of 59.3 kDa after removal of the signal peptide.
    基因ID
    10232
    UniProt
    Q13421
    途径
    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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