IL3RA Protein (AA 19-305) (Fc-His Tag)
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- 抗原 See all IL3RA 蛋白
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-305
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL3RA protein is labelled with Fc-His Tag.
- 应用范围
- ELISA
- 原理
- Recombinant human CD123 protein with C-terminal human Fc and 6xHis tag
- 特异性
- CD123 (Thr19-Arg305) hFc (Glu99-Ala330) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IL3RA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- 别名
- CD123 (IL3RA 产品)
- 别名
- CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
- 背景
- Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor a chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells
- 分子量
- predicted molecular mass of 80-90 kDa after removal of the signal peptide.
- 基因ID
- 3563
- UniProt
- P26951
- 途径
- JAK/STAT Signaling
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