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SARS-CoV-2 Spike S2 Protein (His tag)

宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. SDS
产品编号 ABIN6952626
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike S2 蛋白
    SARS-CoV-2 Spike S2
    蛋白类型
    Recombinant
    宿主
    • 16
    • 3
    • 1
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    资源
    • 13
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This SARS-CoV-2 Spike S2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    原理
    SARS-CoV-2 (COVID-19) S2 protein, His Tag
    序列
    AA 686-1213
    产品特性
    SARS-CoV-2 S2 protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). Predicted N-terminus: Ser 686
    This protein carries a polyhistidine tag at the C-terminus.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SARS-CoV-2 Spike S2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    For long term storage, the product should be stored at lyophilized state at -20°C or lower.
    This product is stable after storage at:
    4-8°C for 12 months in lyophilized state,
    -70°C for 3 years under sterile conditions after reconstitution.
  • Longworth, Dittmar: "An antigen microarray protocol for COVID-19 serological analysis." in: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).

    Tosif, Neeland, Sutton, Licciardi, Sarkar, Selva, Do, Donato, Quan Toh, Higgins, Van de Sandt, Lemke, Lee, Shoffner, Flanagan, Arnold, Mordant, Mulholland, Bines, Dohle, Pellicci, Curtis, McNab et al.: "Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19. ..." in: Nature communications, Vol. 11, Issue 1, pp. 5703, (2020) (PubMed).

    Wei, Wan, Yan, Wang, Zhang, Yang, Zhang, Fan, Li, Deng, Sun, Gong, Yang, Wang, Wang, Li, Yang, Li, Zhang, Wang, Du, Zong, Yin, Zhang, Wang, Peng, Lin, Feng, Qin, Chen, Gao, Zhang, Cao, Zhong: "HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry." in: Nature metabolism, Vol. 2, Issue 12, pp. 1391-1400, (2020) (PubMed).

  • 抗原
    SARS-CoV-2 Spike S2
    Abstract
    SARS-CoV-2 Spike S2 产品
    别名
    E2 Protein, Surface Glycoprotein Protein, S Protein
    物质类
    Viral Protein
    背景
    It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    分子量
    60.0 kDa
    基因ID
    43740568
    UniProt
    P0DTC2
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