IL17C Protein (AA 19-197) (His tag)
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- 抗原 See all IL17C 蛋白
- IL17C (Interleukin 17C (IL17C))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 19-197
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL17C protein is labelled with His tag.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL17C 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- IL17C (Interleukin 17C (IL17C))
- 别名
- IL-17C (IL17C 产品)
- 别名
- IL17C Protein, il17-3 Protein, CX2 Protein, IL-17C Protein, IL-21 Protein, interleukin 17C Protein, interleukin 17c Protein, IL17C Protein, il17c Protein, Il17c Protein
- 背景
- Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL-17C binds to IL-17 RE with high affinity and to IL-17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
- 分子量
- 21.6 kDa
- NCBI登录号
- NP_037410
- 途径
- Cellular Response to Molecule of Bacterial Origin
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