CD70 Protein (AA 52-193) (Fc Tag)
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- 抗原 See all CD70 蛋白
- CD70 (CD70 Molecule (CD70))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 52-193
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD70 protein is labelled with Fc Tag.
- 序列
- AA 52-193
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD70 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris, Glycine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- CD70 (CD70 Molecule (CD70))
- 别名
- CD27 Ligand (CD70 产品)
- 别名
- CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
- 背景
- Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.
- 分子量
- 74.1 kDa
- NCBI登录号
- NP_001243
- 途径
- Cancer Immune Checkpoints
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