CXCL12 Protein (AA 24-89) (Biotin)
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- 抗原 See all CXCL12 蛋白
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-89
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CXCL12 protein is labelled with Biotin.
- 应用范围
- Flow Cytometry (FACS), Cell Migration Assay (CMA)
- 序列
- KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
- 产品特性
- Biotininylated Recombinant Human CXCL12 (SDF-1alpha)
- 纯度
- > 97 % by SDS PAGE
- 内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
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EC50 = 0.5-0.9 nM determined by Calcium Flux with human CXCR4 in U937 cells
Migration confirmed with U937 cells expressing CXCR4 - Top Product
- Discover our top product CXCL12 蛋白
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Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 23-89) (Active) protein (His tag,GST tag)
CXCL12 宿主: 人 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-93) protein (His tag)CXCL12 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) protein (His tag)CXCL12 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) protein (His tag)CXCL12 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 1-89) protein (GST tag)CXCL12 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) proteinCXCL12 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- 储存条件
- -20 °C,-80 °C
- 储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - 有效期
- 12 months
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- 抗原
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
- 别名
- CXCL12/SDF-1alpha (CXCL12 产品)
- 背景
- Stromal-Cell Derived Factor-1alpha (SDF-1alpha) (CXCL12) attracts lymphocytes and plays important roles in embryogenesis and angiogenesis with implications in tumor metastasis. By binding to CXCR4, one of the co-receptors for HIV viral entry, SDF-1alpha can suppress HIV. Besides CXCR4, SDF-1alpha also binds to the “decoy” receptor CXCR7, and activates the downstream beta-arrestin- rather than G protein-mediated signaling pathway.
- 分子量
- 10.381 kDa
- UniProt
- P48061
- 途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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