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CCL3 Protein (AA 24-92) (Biotin)

CCL3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % by SDS PAGE CMA Active
产品编号 ABIN6952184
发货至: 中国
  • 抗原 See all CCL3 蛋白
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-92
    宿主
    • 19
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    资源
    • 23
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CCL3 protein is labelled with Biotin.
    应用范围
    Cell Migration Assay (CMA)
    序列
    SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
    产品特性
    Biotininylated Recombinant Human CCL3 (MIP-1alpha)
    纯度
    > 97 % by SDS PAGE
    内毒素水平
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 1.1-2.6 nM determined by Migration Assay of recombinant CCR5 containing cells
    Top Product
    Discover our top product CCL3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    储存条件
    -20 °C,-80 °C
    储存方法
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    有效期
    12 months
  • 抗原
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    别名
    CCL3 (MIP-1alpha) (CCL3 产品)
    别名
    MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
    背景
    Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
    分子量
    10.135 kDa
    UniProt
    P10147
    途径
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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