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CCL2 Protein (AA 24-99)

CCL2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % by SDS PAGE CMA Active
产品编号 ABIN6952165
发货至: 中国
  • 抗原 See all CCL2 蛋白
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-99
    宿主
    • 17
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 31
    • 10
    • 9
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Cell Migration Assay (CMA)
    序列
    QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSIDHLDKQ TQTPKT
    产品特性
    Recombinant Human CCL2 (MCP-1)
    纯度
    > 97 % by SDS PAGE
    内毒素水平
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 0.067nM determined by Migration Assay of recombinant CCR2 containing cells
    Top Product
    Discover our top product CCL2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    储存条件
    -20 °C,-80 °C
    储存方法
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    有效期
    12 months
  • 抗原
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    别名
    CCL2 (MCP-1) (CCL2 产品)
    别名
    GDCF-2 Protein, HC11 Protein, HSMCR30 Protein, MCAF Protein, MCP-1 Protein, MCP1 Protein, SCYA2 Protein, SMC-CF Protein, AI323594 Protein, JE Protein, Scya2 Protein, Sigje Protein, MCP-1A Protein, MCP1A Protein, C-C motif chemokine ligand 2 Protein, chemokine (C-C motif) ligand 2 Protein, C-C motif chemokine 2 Protein, CCL2 Protein, Ccl2 Protein, LOC101120093 Protein
    背景
    Monocyte chemoattractant protein-1 (MCP-1) (CCL2) is produced by many cell types at sites of inflammation. It regulates chemotaxis and transendothielial migration of monocytes, as well as memory T cells and natural killer cells by interacting with their membrane surface receptor CCR2. MCP-1 has also been implicated in a number of disease states, such as rheumatoid arthritis, psoriasis, atherosclerosis, autoimmune diseases, tumor progression, and HIV infection. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It binds to chemokine receptors CCR2 and CCR4.
    分子量
    8.662 kDa
    UniProt
    P13500
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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