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SIGLEC10 Protein (AA 17-546) (His tag,AVI tag,Biotin)

SIGLEC10 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN6938925
发货至: 中国
  • 抗原 See all SIGLEC10 蛋白
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    蛋白类型
    Recombinant
    产品特性
    AA 17-546
    宿主
    • 19
    • 3
    • 2
    资源
    • 17
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This SIGLEC10 protein is labelled with His tag,AVI tag,Biotin.
    序列
    AA 17-546
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SIGLEC10 蛋白
  • 说明

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS with Arginine,  pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    别名
    Siglec-10 (SIGLEC10 产品)
    别名
    PRO940 Protein, SIGLEC-10 Protein, SLG2 Protein, Siglecg Protein, SIGLEC10 Protein, slg2 Protein, pro940 Protein, siglec-10 Protein, sialic acid binding Ig like lectin 10 Protein, sialic acid binding Ig-like lectin 10 Protein, sialic acid-binding Ig-like lectin 10 Protein, SIGLEC10 Protein, Siglec10 Protein, LOC484343 Protein, LOC100066644 Protein, siglec10 Protein, LOC100513863 Protein, LOC100340374 Protein
    背景
    The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
    分子量
    61.8 kDa
    NCBI登录号
    NP_149121
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