SIGLEC8 Protein (AA 17-363) (His tag)
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- 抗原 See all SIGLEC8 蛋白
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- 蛋白类型
- Recombinant
- 产品特性
- AA 17-363
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SIGLEC8 protein is labelled with His tag.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SIGLEC8 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS with Arginine, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- 别名
- Siglec-8 (SIGLEC8 产品)
- 别名
- SAF2 Protein, SIGLEC-8 Protein, SIGLEC8L Protein, SIGLEC8 Protein, sialic acid binding Ig like lectin 8 Protein, sialic acid-binding Ig-like lectin 8 Protein, SIGLEC8 Protein, LOC506364 Protein
- 背景
- Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.
- 分子量
- 39.7 kDa
- NCBI登录号
- NP_002072
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