IL-17A/F 蛋白
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- 抗原 See all IL-17A/F 蛋白
- IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- Supplier Product No.
- 009-001-v56-0005
- Supplier
- Rockland
- 原理
- Human Interleukin-17AF Heterodimer Recombinant Protein
- 纯化方法
- Interleukin-17AF Heterodimer purity was determined to be greater than 98% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
- 纯度
- 98,00%
- 内毒素水平
- Measured by LAL is typically ≤ 1 EU/μg protein.
- Biological Activity Comment
- The activity is determined by a dose-dependent production of IL-6 in cultured mouse NIH 3T3 fibroblasts and is typically 3-15 ng/mL.
- Top Product
- Discover our top product IL-17A/F 蛋白
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Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 26-158) protein (His-Avi Tag)
IL-17A/F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 26-158) protein (His-Avi Tag,Biotin)IL-17A/F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) protein (His-Avi Tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag,AVI tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
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- 应用备注
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Other: User Optimized
Application_Note: Interleukin-17AF Heterodimer Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-17AF Heterodimer in immunological assays.
- 说明
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Suggested_Applications: Cellular Assay
Other_Performance_Data:
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 5 μL (5-50 μL)
- 缓冲液
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Buffer: 0.1 % Trifluoroacetic acid
Stabilizer: None
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- 有效期
- 6 months
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- 抗原
- IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
- 别名
- IL17A/IL17F (IL-17A/F 产品)
- 背景
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Synonyms: IL17 heterodimer, IL17AF heterodimer, CTLA-8 ML-1 dimer, Interleukin 17AF, Interleukin-17AF heterodimer
Background: Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17RA receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells. Recombinant human IL-17AF is a non-glycosylated heterodimer, containing one IL-17A subunit and one IL-17F subunit. The dimer has a total of 271 amino acids, with an approximate molecular weight of 30.7 kDa.
- UniProt
- Q16552
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