MAPT Protein (Pro301Ser-Mutant)
(1 reference)
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- 抗原 See all MAPT 蛋白
- MAPT (Microtubule-Associated Protein tau (MAPT))
- 蛋白类型
- Recombinant
- 产品特性
- Pro301Ser-Mutant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Western Blotting (WB)
- Supplier Product No.
- 009-001-u01s
- Supplier
- Rockland
- 原理
- Tau-441 (P301S) recombinant protein
- 纯化方法
- Recombinant human tag-free Tau-441 (P301S) was expressed in E. coli cells. The purity was determined to be >90% by densitometry.
- 纯度
- >90%
- Top Product
- Discover our top product MAPT 蛋白
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Microtubule-Associated Protein tau (MAPT) (Transcript Variant 6) protein (His tag)
MAPT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Microtubule-Associated Protein tau (MAPT) (AA 2-752), (full length) protein (His tag)MAPT 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
Microtubule-Associated Protein tau (MAPT) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)MAPT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Microtubule-Associated Protein tau (MAPT) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)MAPT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Microtubule-Associated Protein tau (MAPT) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)MAPT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Western_Blot_Dilution: User Optimized
Other: Kinase Assay-User Optimized
Application_Note: Tau-441 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~63 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
- 说明
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EM
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 μg/μL
- 缓冲液
- Tau-441 Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 有效期
- 12 months
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: "Trans-seeding of Alzheimer-related tau protein by a yeast prion." in: Alzheimer's & dementia : the journal of the Alzheimer's Association, Vol. 18, Issue 12, pp. 2481-2492, (2023) (PubMed).
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: "Trans-seeding of Alzheimer-related tau protein by a yeast prion." in: Alzheimer's & dementia : the journal of the Alzheimer's Association, Vol. 18, Issue 12, pp. 2481-2492, (2023) (PubMed).
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- 抗原
- MAPT (Microtubule-Associated Protein tau (MAPT))
- 别名
- MAPT (MAPT 产品)
- 背景
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Synonyms: Tau-F, (N2R4), Tau-4, MAPT, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, FLJ31424, MGC138549, Microtubule-associated protein tau
Background: Tau-441 or Tau-F is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules (1). Deposits of Alzheimer's disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as, β-amyloid precursor protein (βAPP), ubiquitin, and various chaperones and protein kinases are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system (2). Tau-441 Protein is ideal for investigators involved in Signaling Proteins, Tau Proteins, Invasion/Metastasis, Neurobiology, and p38 Pathway research.
- UniProt
- P10636-8
- 途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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