Neurotrophin 4 Protein (NTF4)
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- 抗原 See all Neurotrophin 4 (NTF4) 蛋白
- Neurotrophin 4 (NTF4)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- Supplier Product No.
- 009-001-w07-0100
- Supplier
- Rockland
- 原理
- Human Neurotrophin-4 Recombinant Protein
- 纯化方法
- Neurotrophin-4 purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
- 纯度
- 97,00%
- 内毒素水平
- Measured by LAL is typically ≤ 1 EU/μg protein.
- Biological Activity Comment
- Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6) ED50 ≤ 20 ng/mL (≥ 5.0 x 10^4 units/mg).
- Top Product
- Discover our top product NTF4 蛋白
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- 应用备注
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Other: User Optimized
Application_Note: Neurotrophin-4 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Neurotrophin-4 in immunological assays.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
- 缓冲液
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Buffer: 0.1 % Trifluoroacetic acid
Stabilizer: None
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- 有效期
- 6 months
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- 抗原
- Neurotrophin 4 (NTF4)
- 别名
- NTF4 (NTF4 产品)
- 背景
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Synonyms: Neurotrophin 5 (NT-5), Neurotrophic Factor 4
Background: Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins along with NT-3, BDNF and NGF. Neurotrophins act in a paracrine and/or autocine manner to control neuronal numbers and dendrite outgrowth. These functions are thought to be communicated by TrkB, a receptor tryrosine kinase that NT-4 shares with BDNF. Recombinant human NT-4 is a non-glycosylated, non-covalently linked homodimer, containing two 131 amino acid chains, with a total molecular weight of 28.1 kDa.
- UniProt
- P34130
- 途径
- RTK signaling
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