IL-21 蛋白
-
- 抗原 See all IL-21 (IL21) 蛋白
- IL-21 (IL21) (Interleukin 21 (IL21))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS)
- Supplier Product No.
- 009-001-v61-0010
- Supplier
- Rockland
- 原理
- Human Interleukin-21 Recombinant Protein
- 纯化方法
- Interleukin-21 purity was determined to be greater than 95% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
- 纯度
- 95,00%
- 内毒素水平
- Measured by LAL is typically ≤ 1 EU/μg protein.
- Biological Activity Comment
- The activity is determined by the dose-dependent stimulation of B9 cells and is typically less than 50 ng/mL.
- Top Product
- Discover our top product IL21 蛋白
-
-
- 应用备注
-
Other: User Optimized
Application_Note: Interleukin-21 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-21 in immunological assays.
- 说明
-
Suggested_Applications: Cellular Assay
Other_Performance_Data:
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
-
Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 10 μL (10-100 μL)
- 缓冲液
-
Buffer: 0.01 M Sodium Phosphate, pH 7.5
Stabilizer: None
- 储存液
- Without preservative
- 储存条件
- -20 °C
- 储存方法
- Store vial at -20° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- 有效期
- 6 months
-
- 抗原
- IL-21 (IL21) (Interleukin 21 (IL21))
- 别名
- IL21 (IL21 产品)
- 背景
-
Synonyms: Za11
Background: Interleukin-21 (IL-21) is a member of the common gamma-chain family of cytokines (includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15) and is expressed by activated CD4+ T cells. IL-21 has a private receptor known as IL-21R, which is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and cooperates with IL-4 for the production of multiple Ab classes in vivo. Initial studies have demonstrated that IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, natural killer, and dendritic cells. Recombinant human IL-21 is a non-glycosylated protein, containing 133 amino acids, with a total molecular weight of 15.5 kDa.
- UniProt
- Q9HBE4
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
-