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IL1A 蛋白

Rockland 009-001-v24-0010 IL1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant 97,00% SDS
Rockland
产品编号 ABIN6699985
Supplier Product No.: 009-001-v24-0010
发货至: 中国
  • 抗原 See all IL1A 蛋白
    IL1A (Interleukin 1 alpha (IL1A))
    蛋白类型
    Recombinant
    宿主
    • 16
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    资源
    • 37
    • 13
    • 11
    • 2
    • 1
    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    Supplier Product No.
    009-001-v24-0010
    Supplier
    Rockland
    原理
    Human Interleukin-1-alpha Recombinant Protein
    纯化方法
    Interleukin-1-alpha purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
    纯度
    97,00%
    内毒素水平
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Biological Activity Comment
    The activity is determined by the stimulation of D10S.G4.1 cells and is typically 1-6 pg/mL.
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    Discover our top product IL1A 蛋白
  • 应用备注

    Other: User Optimized

    Application_Note: Interleukin-1-alpha Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-1-alpha in immunological assays.

    说明

    Suggested_Applications: Cellular Assay

    Other_Performance_Data:

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 10 μL (10-100 μL)

    缓冲液

    Buffer: 0.01 M Sodium Phosphate, pH 7.5

    Stabilizer: None

    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    有效期
    6 months
  • 抗原
    IL1A (Interleukin 1 alpha (IL1A))
    别名
    IL1A (IL1A 产品)
    背景

    Synonyms: IL-1F1, FAF, BAF, LEM, LAF, Hematopoietin-1

    Background: Interleukin-1 alpha (IL-1α) is constitutively expressed by epithelial cells, but can also be produced by most other cells upon stimulation. IL-1β and IL-1α are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1α is cell associated and IL-1β is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant human IL-1α is a non-glycosylated single chain protein, containing 159 amino acids, with a molecular weight of 18 kDa.

    UniProt
    P01583
    途径
    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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