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IGF1 蛋白

Rockland 010-001-v21-0010 IGF1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant 98,00% SDS
Rockland
产品编号 ABIN6699966
Supplier Product No.: 010-001-v21-0010
发货至: 中国
  • 抗原 See all IGF1 蛋白
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    蛋白类型
    Recombinant
    宿主
    • 27
    • 14
    • 10
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 49
    • 15
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    Supplier Product No.
    010-001-v21-0010
    Supplier
    Rockland
    原理
    Mouse Insulin-like Growth Factor I Recombinant Protein
    纯化方法
    Insulin-like Growth Factor I purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
    纯度
    98,00%
    内毒素水平
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Biological Activity Comment
    The activity is determined by the dose-dependent proliferation of FDC-P1 cells and is typically less than 20 ng/mL.
    Top Product
    Discover our top product IGF1 蛋白
  • 应用备注

    Other: User Optimized

    Application_Note: Insulin-like Growth Factor I Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Insulin-like Growth Factor I in immunological assays.

    说明

    Suggested_Applications: Cellular Assay

    Other_Performance_Data:

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 10 μL (10-100 μL)

    浓度
    0.1 mg/mL
    缓冲液

    Buffer: 0.1 % Trifluoroacetic acid

    Stabilizer: None

    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    有效期
    6 months
  • 抗原
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    别名
    Igf1 (IGF1 产品)
    背景

    Synonyms: Somatamedin C, mechano growth factor, IGF-IA

    Background: Insulin-like Growth Factor I, IGF-I, is a growth factor produced in response to growth hormone-stimulated liver and can be found circulating throughout the body and throughout life. IGF-I activates the IGF-I receptor (IGF1R) and the insulin receptor to mediate growth of almost every cell of the body. IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. Mature human IGF-I is 100 % homologous with bovine and porcine proteins. Recombinant mouse IGF-I is a non-glycosylated protein, containing 70 amino acids, with a molecular weight of 7.6 kDa.

    UniProt
    Q8CAR0
    途径
    RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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