FGF4 蛋白
-
- 抗原 See all FGF4 蛋白
- FGF4 (Fibroblast Growth Factor 4 (FGF4))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 应用范围
- Western Blotting (WB)
- Supplier Product No.
- 009-001-f50s
- Supplier
- Rockland
- 原理
- HSF1 recombinant protein
- 纯化方法
- Recombinant full length human HSF1 was expressed in E.coli cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.
- 纯度
- >90%
- Top Product
- Discover our top product FGF4 蛋白
-
Fibroblast Growth Factor 4 (FGF4) protein
FGF4 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by reducing SDS-PAGE.
Fibroblast Growth Factor 4 (FGF4) (AA 71-206) protein (His tag)FGF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Fibroblast Growth Factor 4 (FGF4) (AA 25-206) protein (His tag)FGF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 4 (FGF4) proteinFGF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
-
- 应用备注
-
Western_Blot_Dilution: User Optimized
Other: Kinase Assay-User Optimized
Application_Note: HSF1 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~96 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.2 μg/μL
- 缓冲液
- HSF1 Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- FGF4 (Fibroblast Growth Factor 4 (FGF4))
- 别名
- FGF4 (FGF4 产品)
- 背景
-
Synonyms: Heat Shock Transcription Factor 1, HSTF1, Fibroblast growth factor 4, Heparin secretory-transforming protein 1, Heparin-binding growth factor 4, Transforming protein KS3, FGF-4, HSTF-1, HST, Transforming protein KS3
Background: HSF1 is a member of the heat shock transcription factor family. Protein-damaging stress lead to the activation of HSF1 which binds to upstream regulatory sequences in the promoters of heat shock genes leading to enhanced heat shock gene expression (1). The activation of HSF1 proceeds through a multi-step pathway, involving a monomer-to-trimer transition, nuclear accumulation and extensive posttranslational modifications. HSF1 activity is regulated at different levels by heat shock proteins and co-chaperones and is modulated further by a number of mechanisms involving other stress-regulated aspects of cell metabolism (2). HSF1 Protein is ideal for investigators involved in Signaling Proteins, Transcription Proteins, Cancer, Cardiovascular Disease, Cellular Stress, Inflammation, and JNK/SAPK Pathway research.
- NCBI登录号
- NM_005526
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance
-
