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- 抗原 See all CCL19 蛋白
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- Supplier Product No.
- 010-001-c21
- Supplier
- Rockland
- 原理
- MIP-3ß Mouse Recombinant Protein
- 纯化方法
- Purity was determined to be greater than 98% as determined by reducing and non-reducing SDS-PAGE and analytical HPLC.
- 纯度
- 98,00%
- 内毒素水平
- Measured by LAL is < 0.01 ng/μg or < 0.1 EU/μg protein.
- Biological Activity Comment
- Recombinant mouse MIP-3-beta induces chemotaxis of human T- cells in a concentration range of 8 - 80 ng/ml.
- Top Product
- Discover our top product CCL19 蛋白
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Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (T7 tag)
CCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 26-108) protein (His tag)CCL19 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) (Active) proteinCCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 1-98) protein (GST tag)CCL19 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (Fc Tag)CCL19 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) (Active) protein (Biotin)CCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % by SDS PAGE CMA Active
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- 应用备注
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Other: User Optimized
Application_Note: MIP-3ß protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-MIP-3ß in immunological assays.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 20 μL (20-200 μL)
- 浓度
- 0.1 μg/mL
- 缓冲液
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Buffer: 0.1 % Trifluoroacetic acid
Stabilizer: None
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL) . For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- 有效期
- 6 months
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- 抗原
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- 别名
- Ccl19 (CCL19 产品)
- 背景
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Synonyms: C-C motif chemokine 19, Small-inducible cytokine A19, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, ELC
Background: Macrophage Inflammatory Protein-3-beta (CCL 19, of the intercrine beta chemokine CC family) is an important secreted chemoattractant for dendritic cells, antigen-engaged B-cells, and effector-memory T-cells, signaling through the CCR7 receptor. It may play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. MIP-3ß specifically binds to chemokine receptor CCR7. MIP-3ß is strongly chemotactic for naive CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory CD4 T-cells. There is significant expression in dendritic cells in mesenteric and peripheral lymph nodes, and in spleen (T-cell zone or periarteriolar lymphatic sheath) and Peyer patches, but low expression in thymus. Recombinant mouse MIP-3-beta is a polypeptide chain consisting of 83 amino acids with a molecular weight of 9,200 Daltons.
- UniProt
- O70460
- 途径
- Positive Regulation of Immune Effector Process
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