BAG1 Protein (GST tag)
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- 抗原 See all BAG1 蛋白
- BAG1 (BCL2-Associated Athanogene (BAG1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This BAG1 protein is labelled with GST tag.
- 应用范围
- Western Blotting (WB)
- Supplier Product No.
- 009-001-r46s
- Supplier
- Rockland
- 原理
- BAG1 recombinant protein-GST fusion protein
- 纯化方法
- Recombinant human BAG1 (72-end) was expressed in E. coli cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >85% by densitometry.
- 纯度
- >85%
- Top Product
- Discover our top product BAG1 蛋白
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BCL2-Associated Athanogene (BAG1) (AA 241-345) protein (GST tag)
BAG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
BCL2-Associated Athanogene (BAG1) (AA 1-274) protein (GST tag)BAG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
BCL2-Associated Athanogene (BAG1) (AA 1-230) proteinBAG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
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- 应用备注
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Western_Blot_Dilution: User Optimized
Application_Note: BAG1 Protein is suitable for use in Western Blot. Expect a band approximately ~ 66 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 μg/μL
- 缓冲液
- BAG1 Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- BAG1 (BCL2-Associated Athanogene (BAG1))
- 别名
- BAG1 (BAG1 产品)
- 背景
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Synonyms: BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1), HAP, RAP46
Background: BAG1 (also known as BCL2-associated athanogene) is a membrane protein rich in glutamic acid residues that binds to BCL2 and blocks apoptosis or programmed cell death (1). The BAG1-BCL2 complex enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms (2). Overexpression of BAG1 in 3T3 fibroblasts prevents apoptosis in the presence of low serum. BAG1 has also been shown to interact with activated glucocorticoid, androgen, estrogen and progesterone receptors. Binding to these receptors by BAG1 is dependent on receptor activation. BAG1 Protein is ideal for investigators involved in Signaling Proteins, Apoptosis Proteins, AKT/PKB Pathway, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, and Neurobiology research.
- NCBI登录号
- NM_004323
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