si:zc215i13.3 Protein, si:ch211-215i13.3 Protein, BAALC Protein, 2810457D07Rik Protein, BAALC, MAP3K1 and KLF4 binding Protein, brain and acute leukemia, cytoplasmic Protein, BAALC Protein, baalc Protein, Baalc Protein
背景
Brain and acute leukemia, cytoplasmic (BAALC) is localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKIIalpha and is thought to play a role in synaptic function at postsynaptic lipid rafts. Overexpression of BAALC concomitant predict adverse clinical outcome and may define important risk factor in cytogenetically normal acute myeloid leukemia (AML). Recombinant human BAALC, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: , Brain and acute leukemia, cytoplasmic isoform 1 Brain and acute leukemia cytoplasmic, FLJ12015. NCBI no.: NP_079088