Nanog Protein (AA 1-305)
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- 抗原 See all Nanog (NANOG) 蛋白
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- 产品特性
- AA 1-305
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- NANOG, 1-305aa, Human, E.coli
- 纯度
- > 90 % by SDS - PAGE
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 5% glycerol
- 储存条件
- 4 °C
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- 抗原
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- 别名
- NANOG (NANOG 产品)
- 背景
- Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Synonyms: Nanog homeobox, Homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48. NCBI no.: NP_079141
- 分子量
- 34.6 kDa (305aa)
- 途径
- Stem Cell Maintenance
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