FKBP-13 Protein, PPIase Protein, FKBP12 Protein, Fkbp2 Protein, 13kDa Protein, FKBP-2 Protein, mFKBP13 Protein, mFKBP2 Protein, RGD1560660 Protein, zgc:101826 Protein, FK506 binding protein 2 Protein, FK506 binding protein 1a Protein, FK506 binding protein 2 L homeolog Protein, FKBP2 Protein, Fkbp1a Protein, Fkbp2 Protein, fkbp2 Protein, fkbp2.L Protein
背景
FKBP2 is peptidyl proline isomerase enzyme and a member of the immunophilin protein family. This protein is predominantly expressed in thymus and T cells and plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Recombinant FKBP2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FKBP-13, PPIase, Peptidyl-prolyl cis-trans isomerase FKBP2 13 kDa FKBP, EC 5.2.1.8, FK506 binding protein 2 (13kD), FK506 binding protein 2 13kDa, FKBP 13, FKBP 2, FKBP13, Peptidyl prolyl cis trans isomerase, Proline isomerase, Rapamycin binding protein, Rotamase. NCBI no.: NP_001128680