PNMT, also known as phenylethanolamine N-methyltransferase, is an enzyme found in the adrenal medulla that catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Recombinant PNMT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PENT, PNMTase, Noradrenaline-N-methyltransferase, Phenylethanolamine N-methyltransferase. NCBI no.: NP_002677