SPR Protein (AA 1-261) (His tag)
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- 抗原 See all SPR 蛋白
- SPR (Sepiapterin Reductase (SPR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-261
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This SPR protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- Sepiapterin reductase, 1-261 aa, Human, His-tagged, Recombinant, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SPR 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
- 储存条件
- 4 °C
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- 抗原
- SPR (Sepiapterin Reductase (SPR))
- 别名
- Sepiapterin reductase (SPR 产品)
- 别名
- SDR38C1 Protein, AA409688 Protein, ENSMUSG00000071345 Protein, Gm10328 Protein, CG12117 Protein, Dmel\\CG12117 Protein, SR Protein, sptr Protein, xspr Protein, DDBDRAFT_0188686 Protein, DDBDRAFT_0191275 Protein, DDB_0188686 Protein, DDB_0191275 Protein, zgc:194446 Protein, sepiapterin reductase Protein, Sepiapterin reductase Protein, sepiapterin reductase L homeolog Protein, sepiapterin reductase b Protein, SPR Protein, Spr Protein, Sptr Protein, spr.L Protein, sprE Protein, CpipJ_CPIJ000511 Protein, sr Protein, spr Protein, sprb Protein
- 背景
- Sepiapterin reductase (SPR) belongs to the short-chain dehydrogenase/reductase (SDR) family and also reduces various exogenous carbonyl compounds including phenylpropanedione. SPR is an essential enzyme for the biosynthesis of tetrahydrobiopterin, an essential cofactor for aromatic amino acid hydrolases including tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. Defects in SPR cause DOPA-responsive dystonia defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Recombinant human SPR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: SPR, Sepiapterin reductase. NCBI no.: NP_003115
- 分子量
- 30.2 kDa (281aa), confirmed by MALDI-TOF.
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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