COMT Protein (AA 51-271)
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- 抗原 See all COMT 蛋白
- COMT (Catechol-O-Methyltransferase (COMT))
- 蛋白类型
- Recombinant
- 产品特性
- AA 51-271
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- COMT, 51-271 aa, Human, Recombinant, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product COMT 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM MgCl2, 10% glycerol
- 储存条件
- 4 °C
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- 抗原
- COMT (Catechol-O-Methyltransferase (COMT))
- 别名
- COMT (COMT 产品)
- 背景
- Catechol-O-methyltrasferase (COMT) is an enzyme that catalyses the transfer of the methyl group of S-adenosylmethionine (SAM) into catechol substrates such as levodopa, dopamine, epinephrine, and norepinephirine in the presence of Mg2+. COMT appears to be located in the postsynaptic neuron and plays roles in the metabolism of catechol estrogens and the inactivation of catecholamine neurotransmitters though enzymatic degradation. COMT inhibitors prevent levodopa degradation, increase its availability and are used in the treatment of patients with Parkinson's disease. Recombinant human COMT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Catechol-O-methyltransferase , Catechol-O-methyltransferase , COMT. NCBI no.: NP_000745
- 分子量
- 24.4 kDa (221 aa), confirmed by MALDI-TOF.
- 途径
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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