Quick Overview for PIN1 蛋白 (ABIN666676)
抗原
See all PIN1 蛋白宿主
资源
应用范围
纯度
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产品特性
- Pin 1(Peptidyl-prolyl cis/trans isomerase) Human, Recombinant, E.coli
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 1-165) protein (His tag)
custom-made PIN1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 1-163) protein (His tag)custom-made PIN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 1-163) protein (His tag)PIN1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 1-165) (Active) protein (His tag)PIN1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95% by SDS-PAGE SDS, EAA Active
Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (AA 1-163) protein (GST tag)PIN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml (determined by Bradford assay)
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缓冲液
- Liquid. In 20 mM Tris-HCl buffer(pH7.5) 0.1M NaCl, 5mM DTT, 20%Glycerol.
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储存条件
- 4 °C
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- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
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背景
- Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA ,PLK I, Wee, and Myt1 kinases), several transcription factors like beta-Catenin, c-Jun, and the tumor suppressor protein p53 , and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1. Synonyms: PIN1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, EC 5.2.1.8, Rotamase Pin1, PPIase Pin1, DOD, UBL5, PIN1, PPIase, EC 5.2.1.8, Rotamase Pin1, PPIase Pin1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1. NCBI no.: NP_006212
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分子量
- 18.2 kDa (163 aa), confirmed by MALDI-TOF.
抗原
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