PSG5, also known as pregnancy-specific beta-1-glycoprotein 5, a member of the PSG family that is mainly produced by the placental syncytiotrophoblasts during pregnancy. The function of PSG5 stimulates secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Recombinant human PSG5 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
35.1kDa (310aa) 28-40KDa (SDS-PAGE under reducing conditions.)