NME2 Protein (AA 1-152)
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- 抗原 See all NME2 蛋白
- NME2 (Nucleoside diphosphate kinase B (NME2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-152
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
- 纯度
- > 90 % by SDS - PAGE
- Biological Activity Comment
- Specific activity is > 1,800 units/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25C in a couple system with PK/LDH.
- Top Product
- Discover our top product NME2 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Bioactivity Validated
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- NME2 (Nucleoside diphosphate kinase B (NME2))
- 别名
- NME2 (NME2 产品)
- 别名
- NDKB Protein, NDPK-B Protein, NDPKB Protein, NM23-H2 Protein, NM23B Protein, PUF Protein, nm23-2 Protein, p18-12d Protein, nm23-M2 Protein, NM23-C2 Protein, NME/NM23 nucleoside diphosphate kinase 2 Protein, non-metastatic cells 2, protein (NM23B) expressed in Protein, NME2 Protein, Nme2 Protein
- 背景
- NME2, also known as NM23B, is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways. Recombinant human NME2 protein was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 17.2 kDa (152aa), confirmed by MALDI-TOF
- NCBI登录号
- NP_001018149
- UniProt
- P22392
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