NHEJ1 Protein (His tag)
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- 抗原 See all NHEJ1 蛋白
- NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This NHEJ1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NHEJ1 蛋白
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- 说明
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Synonyms: Non-homologous end-joining factor 1, XLF
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol,1 MM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))
- 别名
- NHEJ1 (NHEJ1 产品)
- 别名
- NHEJ1 Protein, zgc:85657 Protein, XLF Protein, 1700029B21Rik Protein, cernunnos Protein, non-homologous end joining factor 1 Protein, non-homologous end joining factor 1 S homeolog Protein, solute carrier family 23 member 3 Protein, nonhomologous end-joining factor 1 Protein, NHEJ1 Protein, nhej1.S Protein, nhej1 Protein, SLC23A3 Protein, Nhej1 Protein
- 背景
- Non-homologous end-joining factor 1, also known as NHEJ1, belongs to the XLF family. NHEJ1 was originally discovered as the protein mutated in five patients with growth retardation, microcephaly, and immunodeficiency. The protein is required for the non-homologous end joining (NHEJ) pathway of DNA repair. Patients with NHEJ1 mutations also have immunodeficiency due to a defect in V(D)J recombination, which utilizes NHEJ to promote immune system diversity. XLF interacts with DNA ligase IV and XRCC4 and is thought to be involved in the ligation step of NHEJ. Recombinant human NHEJ1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 27.8 kDa (247aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_079058
- 途径
- DNA Damage Repair
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