Liver Arginase Protein (active Mutant)
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- 抗原 See all Liver Arginase (ARG1) 蛋白
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- 蛋白类型
- Recombinant
- 产品特性
- active Mutant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 原理
- Arginase I (human) (rec.) (highly active)
- 特异性
- Full length human arginase I.
- 交叉反应
- 人
- 产品特性
- Full length human arginase I.
- 纯度
- >90 % (SDS-PAGE)
- Biological Activity Comment
- 1.6 ±0.2U/μg protein. One unit is defined as the amount of enzyme that converts 1μmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (according to protocol from R.T. Schimke, et al., J. Biol. Chem. 238, 1012 (1963)).
- Top Product
- Discover our top product ARG1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 μg/μL
- 缓冲液
- In 10 mM TRIS-HCl, pH 7.5, containing 1 mM beta-mercaptoethanol, 1 mM MnCl2 and 50 % glycerol.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 1 year after receipt when stored at -80°C.
- 有效期
- 12 months
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- 抗原
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- 别名
- Arginase I (ARG1 产品)
- 背景
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EC 3.5.3.1, ARG1, Arginase 1, Type I Arginase, Liver-type Arginase, L-Arginase
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
- 分子量
- 34.7kDa
- UniProt
- P05089
- 途径
- Cellular Response to Molecule of Bacterial Origin
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