Liver Arginase Protein (active Mutant)
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- 抗原 See all Liver Arginase (ARG1) 蛋白
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- 蛋白类型
- Recombinant
- 产品特性
- active Mutant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Arginase I (human) (rec.) (highly active)
- 特异性
- Full length human arginase I.
- 产品特性
- Protein. Full length human arginase I. Source: E. coli. Liquid. In 10 mM TRIS-HCl, pH 7.5, containing 1 mM beta-mercaptoethanol, 1 mM MnCl2 and 50 % glycerol. Purity: >90 % (SDS-PAGE). Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
- 纯度
- >90 % (SDS-PAGE)
- Biological Activity Comment
- 1.6 ±0.2U/μg protein. One unit is defined as the amount of enzyme that converts 1μmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (according to protocol from R.T. Schimke, et al.; J. Biol. Chem. 238, 1012 (1963)).
- Top Product
- Discover our top product ARG1 蛋白
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Arginase, Liver (ARG1) (AA 1-322) protein (GST tag)
ARG1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Arginase, Liver (ARG1) protein (MYC tag,His tag)ARG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Arginase, Liver (ARG1) (Active) protein (Myc-DYKDDDDK Tag)ARG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. In 10 mM TRIS-HCl, pH 7.5, containing 1 mM beta-mercaptoethanol, 1 mM MnCl2 and 50 % glycerol.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 1 year after receipt when stored at -80°C.
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- 抗原
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- 别名
- Arginase I (ARG1 产品)
- 背景
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Alternate Names/Synonyms: EC 3.5.3.1, ARG1, Arginase 1, Type I Arginase, Liver-type Arginase, L-Arginase
Product Description: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
- UniProt
- P05089
- 途径
- Cellular Response to Molecule of Bacterial Origin
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