VSIG4 Protein (AA 20-283) (Fc Tag)
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- 抗原 See all VSIG4 蛋白
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-283
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This VSIG4 protein is labelled with Fc Tag.
- 原理
- VSIG4 (human):Fc (mouse) (rec.)
- 特异性
- The extracellular domain of human VSIG4 (aa 20-283) is fused to the N-terminus of the Fc region of mouse IgG2a.
- 产品特性
- Protein. The extracellular domain of human VSIG4 (aa 20-283) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: HEK 293 cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). VSIG4 (V-set and immunoglobulin domain containing 4), as known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Top Product
- Discover our top product VSIG4 蛋白
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V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) (AA 20-283) protein (His tag)
VSIG4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) (AA 25-288) protein (His tag)VSIG4 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) protein (His tag,Fc Tag)VSIG4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) protein (His tag)VSIG4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- 别名
- VSIG4 (VSIG4 产品)
- 别名
- DKFZp468O0322 Protein, CRIg Protein, Z39IG Protein, A530061A11 Protein, BC025105 Protein, V-set and immunoglobulin domain containing 4 Protein, VSIG4 Protein, Vsig4 Protein
- 背景
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Alternate Names/Synonyms: V-set and immunoglobulin domain containing 4, Z39Ig, CRIg
Product Description: VSIG4 (V-set and immunoglobulin domain containing 4), as known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation.
- 分子量
- ~68kDa (SDS-PAGE)
- UniProt
- Q9Y279
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