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Interferon gamma Protein (IFNG) (AA 24-166) (His tag)

IFNG 宿主: 人 宿主: HEK-293 Cells > 95 % CC, AcA Active
产品编号 ABIN6239726
发货至: 中国
  • 抗原 See all Interferon gamma (IFNG) 蛋白
    Interferon gamma (IFNG)
    生物活性
    Active
    产品特性
    AA 24-166
    宿主
    • 22
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    资源
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    HEK-293 Cells
    标记
    This Interferon gamma protein is labelled with His tag.
    应用范围
    Cell Culture (CC), Activity Assay (AcA)
    产品特性
    Tag location: N-terminal His Tag
    纯度
    > 95 %
    Biological Activity Comment
    IFN-γ is a dimerized soluble cytokine that is the only member of the type II class of interferons.The importance of IFNγ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. As reported, IFNγ is an important activator of human monocytic THP1 cells. Therefore,THP-1 cells were incubated in RPMI 1640 with various concentration of IFN-γ , then cells were observed by inverted microscope everyday.After stimulated with IFN-γ(5ng/ml) for 5 days, morphological changes occured in THP1 cells which displayed the shape of fusiform or polygon and were more likely to adhere. Effect of IFN-γ on THP1 cells is shown in Figure 1.
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    Discover our top product IFNG 蛋白
  • 应用备注
    Isoelectric Point: 9.7
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01 % SKL, 5 % Trehalose and Proclin300.
    储存液
    Dithiothreitol (DTT), Other preservative, ProClin
    注意事项
    This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
  • 抗原
    Interferon gamma (IFNG)
    Abstract
    IFNG 产品
    别名
    IFG Protein, IFI Protein, IFN-g Protein, Ifg Protein, IFNG2 Protein, IFN-gamma Protein, IFN-G Protein, IFNG Protein, IFNgamma Protein, TCRalpha Protein, INF-G Protein, ifng Protein, interferon gamma Protein, interferon, gamma 1-2 Protein, IFNG Protein, Ifng Protein, ifng1-2 Protein
    背景
    Alternative Names: IFN-G, IFG, IFI, INFr, IFN, Immune Interferon
    分子量
    22&25kDa
    UniProt
    P01579
    途径
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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