Biglycan Protein (BGN) (AA 38-369) (hIgG-His-tag)
This Recombinant Biglycan protein is expressed in Baculovirus infected Insect Cells.
Quick Overview for Biglycan Protein (BGN) (AA 38-369) (hIgG-His-tag) (ABIN5855132)
抗原
See all Biglycan (BGN) 蛋白
Biglycan (BGN)
蛋白类型
Recombinant
宿主
小鼠
资源
Baculovirus infected Insect Cells
应用范围
SDS-PAGE (SDS)
纯度
> 90% by SDS-PAGE
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产品特性
- AA 38-369
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标记
- This Biglycan protein is labelled with hIgG-His-tag.
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序列
- ADPDEEASGS DTTSGVPDLD SVTPTFSAMC PFGCHCHLRV VQCSDLGLKT VPKEISPDTT LLDLQNNDIS ELRKDDFKGL QHLYALVLVN NKISKIHEKA FSPLRKLQKL YISKNHLVEI PPNLPSSLVE LRIHDNRIRK VPKGVFSGLR NMNCIEMGGN PLENSGFEPG AFDGLKLNYL RISEAKLTGI PKDLPETLNE LHLDHNKIQA IELEDLLRYS KLYRLGLGHN QIRMIENGSL SFLPTLRELH LDNNKLSRVP AGLPDLKLLQ VVYLHSNNIT KVGINDFCPM GFGVKRAYYN GISLFNNPVP YWEVQPATFR CVTDRLAIQF GNYKKLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH
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内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
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Biglycan (BGN) (AA 1-368) protein (GST tag)
BGN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Biglycan (BGN) protein (Fc Tag)BGN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Biglycan (BGN)
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别名
- Biglycan
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背景
- Bgn, also known as biglycan preproprotein, is a small leucine-rich repeat proteoglycan (SLRP). It binds to the growth factors BMP-4 and influences BMP-4 bioactivity. It plays an important role in stabilizing fibrotic scars after experimental myocardial infarction. It may function in connective tissue metabolism by binding to collagen fibrils and TGF-beta and may promote neuronal survival. Its ablation improves cardiac function and attenuates left ventricular hypertrophy and fibrosis after long-term pressure overload. It is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Recombinant mouse Bgn, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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分子量
- 64.6 kDa (574aa)
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NCBI登录号
- NP_031568
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UniProt
- P28653
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途径
- Glycosaminoglycan Metabolic Process
抗原
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