ywha1 Protein, 14-3-3e Protein, YWHAH Protein, YWHA1 Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta L homeolog Protein, YWHAH Protein, ywhah Protein, Ywhah Protein, ywhah.L Protein
背景
14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E.coli and purified by using conventional chromatography techniques.