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MCM7 Protein (AA 1-414) (His tag)

MCM7 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN5853499
发货至: 中国
  • 抗原 See all MCM7 蛋白
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    蛋白类型
    Recombinant
    产品特性
    AA 1-414
    宿主
    资源
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This MCM7 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMVVATYT CDQCGAETYQ PIQSPTFMPL IMCPSQECQT NRSGGRLYLQ TRGSRFIKFQ EMKMQEHSDQ VPVGNIPRSI TVLVEGENTR IAQPGDHVSV TGIFLPILRT GFRQVVQGLL SETYLEAHRI VKMNKSEDDE SGAGELTREE LRQIAEEDFY EKLAASIAPE IYGHEDVKKA LLLLLVGGVD QSPRGMKIRG NINICLMGDP GVAKSQLLSY IDRLAPRSQY TTGRGSSGVG LTAAVLRDSV SGELTLEGGA LVLADQGVCC IDEFDKMAEA DRTAIHEVME QQTISIAKAG ILTTLNARCS ILAAANPAYG RYNPRRSLEQ NIQLPAALLS RFDLLWLIQD RPDRDNDLRL AQHITYVHQH SRQPPSQFEP LDMKLMRRYI AMCREKQPMV PESLADYITA AYVEMRR
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product MCM7 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Denatured

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    别名
    MCM7 (MCM7 产品)
    别名
    CDC47 Protein, MCM2 Protein, P1.1-MCM3 Protein, P1CDC47 Protein, P85MCM Protein, PNAS146 Protein, MCM7 Protein, AI747533 Protein, Mcmd7 Protein, mCDC47 Protein, chunp6911 Protein, nyz175 Protein, sr:nyz175 Protein, cdc47 Protein, cdc47-2 Protein, mcm7 Protein, xmcm7 Protein, CG4978 Protein, DmMCM7 Protein, DmeMCM7 Protein, Dmel\\CG4978 Protein, McM7 Protein, Mcp-PCR1 Protein, PCR1 Protein, anon-EST:Liang-1.66 Protein, clone 1.66 Protein, minichromosome maintenance complex component 7 Protein, mini-chromosome maintenance complex protein 7 Protein, minichromosome maintenance complex component 2 Protein, minichromosome maintenance complex component 7 L homeolog Protein, Minichromosome maintenance 7 Protein, minichromosome maintenance complex component 7 S homeolog Protein, MCM complex subunit Mcm7 Protein, MCM7 Protein, CDC47 Protein, Mcm7 Protein, MCM2 Protein, mcm7 Protein, mcm7.L Protein, mcm7.S Protein
    背景
    MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Recombinant human MCM7 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    48.6kDa (437aa)
    NCBI登录号
    NP_877577
    UniProt
    P33993
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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