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PSTPIP1 Protein (AA 1-416) (His tag)
PSTPIP1
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
> 90 % by SDS - PAGE
SDS
产品细节
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抗原
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PSTPIP1
(Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
蛋白类型
Recombinant
产品特性
AA 1-416
宿主
All origins for PSTPIP1 蛋白
人
资源
All sources for PSTPIP1 蛋白
大肠杆菌(E. Coli)
标记
This PSTPIP1 protein is labelled with His tag.
应用范围
SDS-PAGE (SDS)
序列
MGSSHHHHHH SSGLVPRGSH MGSMMPQLQF KDAFWCRDFT AHTGYEVLLQ RLLDGRKMCK DMEELLRQRA QAEERYGKEL VQIARKAGGQ TEINSLRASF DSLKQQMENV GSSHIQLALT LREELRSLEE FRERQKEQRK KYEAVMDRVQ KSKLSLYKKA MESKKTYEQK CRDADDAEQA FERISANGHQ KQVEKSQNKA RQCKDSATEA ERVYRQSIAQ LEKVRAEWEQ EHRTTCEAFQ LQEFDRLTIL RNALWVHSNQ LSMQCVKDDE LYEEVRLTLE GCSIDADIDS FIQAKSTGTE PPAPVPYQNY YDREVTPLTS SPGIQPSCGM IKRFSGLLHG SPKTTSLAAS AASTETLTPT PERNEGVYTA IAVQEIQGNP ASPAQEYRAL YDYTAQNPDE LDLSAGDILE VILEGEDGWW TVERNGQRGF VPGSYLEKL
纯度
> 90 % by SDS - PAGE
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.5 mg/mL
缓冲液
Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
PSTPIP1
(Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
别名
PSTPIP1 (PSTPIP1 产品 )
别名
cd2bp1 Protein, cd2bp1l Protein, cd2bp1s Protein, h-pip Protein, papas Protein, pstpip Protein, PSTPIP1 Protein, CD2BP1 Protein, CD2BP1L Protein, CD2BP1S Protein, H-PIP Protein, PAPAS Protein, PSTPIP Protein, def-2 Protein, proline-serine-threonine phosphatase interacting protein 1 Protein, proline-serine-threonine phosphatase interacting protein 1 S homeolog Protein, proline-serine-threonine phosphatase-interacting protein 1 Protein, PSTPIP1 Protein, pstpip1.S Protein, pstpip1 Protein, Pstpip1 Protein
背景
PSTPIP1 binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. Recombinant human PSTPIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
分子量
50.0kDa (439aa)
NCBI登录号
NP_003969
UniProt
O43586
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