Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
抗原
ATG16L1
(ATG16 Autophagy Related 16-Like 1 (ATG16L1))
APG16L Protein, ATG16A Protein, ATG16L Protein, IBD10 Protein, WDR30 Protein, 1500009K01Rik Protein, Apg16l Protein, Atg16l Protein, Wdr30 Protein, atg16 Protein, atg16l Protein, fb57e05 Protein, wu:fb57e05 Protein, zgc:110147 Protein, autophagy related 16 like 1 Protein, autophagy related 16-like 1 (S. cerevisiae) Protein, autophagy related 16-like 1 Protein, autophagy related 16 like 1 S homeolog Protein, ATG16 autophagy related 16-like 1 (S. cerevisiae) Protein, ATG16L1 Protein, Atg16l1 Protein, atg16l1 Protein, atg16l1.S Protein
背景
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a mbrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal mbrane.