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- 抗原 See all C4B (C4b) 蛋白
- C4B (C4b) (Complement Component C4b (C4b))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1454-1744
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宿主
- 人
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资源
- 酵母菌
- 标记
- This C4B protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- EAPKVVEEQE SRVHYTVCIW RNGKVGLSGM AIADVTLLSG FHALRADLEK LTSLSDRYVS HFETEGPHVL LYFDSVPTSR ECVGFEAVQE VPVGLVQPAS ATLYDYYNPE RRCSVFYGAP SKSRLLATLC SAEVCQCAEG KCPRQRRALE RGLQDEDGYR MKFACYYPRV EYGFQVKVLR EDSRAAFRLF ETKITQVLHF TKDVKAAANQ MRNFLVRASC RLRLEPGKEY LIMGLDGATY DLEGHPQYLL DSNSWIEEMP SERLCRSTRQ RAACAQLNDF LQEYGTQGCQ V
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product C4b 蛋白
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Complement Component C4b (C4b) (AA 1454-1744) protein (His tag)
C4b 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Complement Component C4b (C4b) (AA 1347-1446) protein (GST tag)C4b 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Complement Component C4b (C4b) (AA 774-873) protein (GST tag)C4b 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- C4B (C4b) (Complement Component C4b (C4b))
- 别名
- CO4B (C4b 产品)
- 别名
- C4B1 Protein, C4B12 Protein, C4B2 Protein, C4B3 Protein, C4B5 Protein, C4BD Protein, C4B_2 Protein, C4F Protein, CH Protein, CO4 Protein, CPAMD3 Protein, C4 Protein, C4A2 Protein, C4A3 Protein, C4A4 Protein, C4A6 Protein, C4AD Protein, C4S Protein, CPAMD2 Protein, RG Protein, wu:fi14a03 Protein, C4B Protein, DKFZP469I0332 Protein, Slp Protein, Ss Protein, C4-2 Protein, C4l Protein, complement C4B (Chido blood group) Protein, complement C4A (Rodgers blood group) Protein, complement component 4 Protein, complement C4-B Protein, complement component 4B (Chido blood group) Protein, complement component 4A (Rodgers blood group) Protein, C4B Protein, C4A Protein, c4 Protein, LOC462577 Protein, C4a Protein, C4b Protein
- 背景
- Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complent pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.Derived from proteolytic degradation of complent C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
- 分子量
- 35.1 kDa
- UniProt
- P0C0L5
- 途径
- Complement System
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