HDAC7 Protein (AA 1-164, partial) (His tag)
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- 抗原 See all HDAC7 蛋白
- HDAC7 (Histone Deacetylase 7 (HDAC7))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-164, partial
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This HDAC7 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- PGADGTQVSP GAHYCSPTGA GCPRPCADTP GPQPQPMDLR VGQRPPVEPP PEPTLLALQR PQRLHHHLFL AGLQQQRSVE PMRLSMDTPM PELQVGPQEQ ELRQLLHKDK SKRSAVASSV VKQKLAEVIL KKQQAALERT VHPNSPGIPY RTLEPLETEG ATRSMLSSFL PPVPSLPSDP PEHFPLRKTV SEPNLKLRYK
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product HDAC7 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- HDAC7 (Histone Deacetylase 7 (HDAC7))
- 别名
- HDAC7 (HDAC7 产品)
- 别名
- HD7A Protein, HDAC7A Protein, 5830434K02Rik Protein, HD7 Protein, HD7a Protein, Hdac7a Protein, mFLJ00062 Protein, hdac7a Protein, K2K18.5 Protein, K2K18_5 Protein, histone deacetylase7 Protein, histone deacetylase 7 Protein, histone deacetylase7 Protein, HDAC7 Protein, Hdac7 Protein, hdac7 Protein, HDA7 Protein
- 背景
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors . May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 .
- 分子量
- 26.1 kDa
- UniProt
- Q8WUI4
- 途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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