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Caspase 3 Protein (CASP3) (AA 29-175, partial) (His tag)

CASP3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5712415
发货至: 中国
  • 抗原 See all Caspase 3 (CASP3) 蛋白
    Caspase 3 (CASP3)
    蛋白类型
    Recombinant
    产品特性
    partial, AA 29-175
    宿主
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 11
    • 9
    • 3
    • 1
    大肠杆菌(E. Coli)
    标记
    This Caspase 3 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    SGISLDNSYK MDYPEMGLCI IINNKNFHKS TGMTSRSGTD VDAANLRETF RNLKYEVRNK NDLTREEIVE LMRDVSKEDH SKRSSFVCVL LSHGEEGIIF GTNGPVDLKK ITNFFRGDRC RSLTGKPKLF IIQACRGTEL DCGIETD
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product CASP3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    Caspase 3 (CASP3)
    别名
    CASP3 (CASP3 产品)
    别名
    CPP32 Protein, CPP32B Protein, SCA-1 Protein, A830040C14Rik Protein, AC-3 Protein, Apopain Protein, CC3 Protein, Caspase-3 Protein, Lice Protein, Yama Protein, mldy Protein, xcpp32 Protein, casp3 Protein, zgc:100890 Protein, CASP-3 Protein, caspase-3 Protein, caspase 3 Protein, caspase 3 S homeolog Protein, caspase 3, apoptosis-related cysteine peptidase a Protein, caspase 3, apoptosis-related cysteine peptidase Protein, CASP3 Protein, Casp3 Protein, casp3.S Protein, casp3a Protein
    背景
    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory elent binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the mbrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
    分子量
    20.7 kDa
    UniProt
    P42574
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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